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Search home ask heartmeds about us advertising disclaimer contact us popular meds ace inhibitors aspirin beta-blockers clopidogrel statins anticoagulation apixaban dabigatran rivaroxaban warfarin pharmacogenomics recent meetings esc 2012 thsna 2012 acc 2012 aha epi/npam 2012 isc 2012 coverage aha 2011 coverage login dashboard profile write an article coronary artery disease heart failure acute decompensated heart failure heart failure with preserved ejection fraction acs myocardial infarction stemi cabg hyperlipidemia diabetes hypertension atrial fibrillation vte vte prophylaxis vte treatment   « selecting an oral anticoagulant in patients with atrial fibrillation: an evidence-based guide for clinicians 10-year exercise training in chronic heart failure » oct 09 does high dose atorvastatin reduce the damage caused by torcetrapib categories: hyperlipidemia by mike dorsch we have talked about this in the past, but the development of the cetp inhibitor, torcetrapib, was halted after the illuminate trial revealed an increase in both all-cause mortality and major cardiovascular events related to its use. buy viagra online There is a new paper explaining the interaction between the atorvastatin dose and torcetrapib. cheap viagra The increase events were primarily in the 10 mg atorvastatin group (hr 2. viagra side effects kidney 68, 95% ci 1. 58-4. 54), p< 0. 0001 for all-cause mortality and hr 1. order viagra 41, 95% ci 1. 14-1. 74), p = 0. viagra side effects kidney 002 for major cardiovascular events. There was no proof of harm when torcetrapib was given with higher doses of atorvastatin. In the atorvastatin 10 mg group, age, prior heart failure and stroke were associated with all-cause mortality, independent of torcetrapib treatment. Low apoa-i, smoking, hypertension, heart failure, myocardial infarction, and stroke were associated with major cardiovascular events. After adjusting for these factors, the association with torcetrapib treatment in the 10 mg atorvastatin group remained significant for both all-cause mortality (hr 2. 67, 95% ci 1. where can i buy generic viagra in canada 57-4. 54), p < 0. viagra samples 001) and major cardiovascular events (hr 1. viagra side effects kidney 36, 95% ci 1. 10-1. 69), p = 0. ingredients viagra pro 005). The damage caused by torcetrapib was in those patients taking atorvastatin 10 mg. order viagra online I don’t know for sure if this really changes anythings. Torcetrapib is still not going to be approved after killing people, but could offer us an insight into the beneficial effects of high dose atorvastatin (or any potent statin) compared to lower doses. This is more data to support that most patients should be on high dose statins. Photo by: t. Lazzara journal of lipid research if you like what you have read, please take a moment to share with others subscribe to our newsletter join the 63 members and subscribe to our newsletter. Add your email below. A confirmation email will be sent to you! Related articles effects of cetp.


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